Hepatocellular carcinoma (HCC)
Risk factors for HCC
- Hepatitis B or hepatitis C infection.
- PBC > PSC
- Alpha-1-antitrypsin deficiency
Investigations in HCC
- Ultrasound scan (USS)
- First line and very sensitive
- Alpha-fetoprotein (AFP)
- If a >2 cm mass is detected on USS and AFP is also raised, this is diagnostic
- Can look for local spread and CT of the thorax can look for metastases.
- MRI or FNA if diagnosis still in doubt
Prognosis in HCC
- Estimated survival based on CLIP score
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